The Brehm Center for Diabetes Research is a high-tech hub for type 1, type 2, obesity, and metabolic disease research.
Basic questions like "Why do some people get type 1 diabetes and others do not?" and "How can we prevent, slow, or even reverse the disease and its effects?" drive the work of the U-M diabetes scientists, who toil late into the night in busy laboratories filled with cell cultures, gene sequencers, high-powered microscopes, and protein analyzers.
Learn about the Preventing Early Renal Loss (PERL) Study for Type 1 Diabetes:
The Brehm Center research team work closely together to foster new knowledge in the lab and translate this into new therapies for patients. The team is represented in all areas of research: basic, translational, and clinical.
The scientists include the Brehm Professors, U-M Brehm Investigators, and Brehm Center Researchers.
The named professorship below was made possible by a generous gift from Bill and Dee Brehm, whose personal mission is to apply the tools of research and analysis to find and deliver a cure for type 1 diabetes.
William K. and Delores S. Brehm Professor of Diabetes Research
Peter Arvan, M.D., Ph.D.
Chief, Division of Metabolism, Endocrinology & Diabetes
Professor of Medicine and Physiology
U-M Brehm Investigators
The U-M Brehm Investigators are a group of U-M researchers (most of them housed in the Brehm Center) that represent a variety of scientific areas. They are designated as "U-M Brehm Investigators" because they bring their unique skills to address the puzzle of type 1 diabetes.
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Brehm Center Researchers
The Brehm Center for Diabetes Research houses a variety of scientists whose focus is to understand, improve, prevent, and cure diabetes. Along with the U-M Brehm Investigators and the Brehm Professors, the rest of the Brehm Center Researchers share resources and collaborate in the Brehm Tower, where the open lab layout and proximity to each other allow for a unique intellectual synergy.
These multidisciplinary scientists represent the specturm of diabetes inquiry: type 1 diabetes, diabetes management, complications of diabetes, and factors leading to type 2 diabetes — such as metabolism and obesity issues. These facets are explored in bench labs with mice and cells, as well as clniical studies with human patients.
Type 1 Diabetes/Animal and Cell Research
Type 2 Diabetes, Metabolism and Obesity
- Charles Burant, MD, PhD
- Malcolm Low, MD, PhD
- Ormond MacDougald, PhD
- Martin Myers, MD, PhD
- Elif Oral, MD
- Subramaniam Pennathur, MD
Diabetes Complications and Management
Pediatric Diabetes, Metabolism and Obesity
The Brehm Coalition is a unique group of senior scientists from across the country devoted to the creation of a new paradigm in medical research based on an unprecedented level and style of laboratory collaboration. Their chosen research pathways are aimed at accelerating the search for a cure for type1 diabetes.
Under the leadership of the Brehm Coalition researchers, over 100 individuals are working to fulfill the Coalition's research mission: to cure type 1 diabetes. Learn more.