Michigan Diabetes Research Center (MDRC)
2022
- Alison Affinati, MD, PhD, Assistant Professor, Internal Medicine - MEND and Joanna Spencer-Segal, MD, PhD, Assistant Professor, Internal Medicine - MEND, “Identifying the neural circuits that underlie hypoglycemia-associated autonomic failure”
2021
- Anuska Andjelkovic-Zochowski, MD, Professor, Pathology and Carol Elias, PhD, Professor, Molecular & Integrative Physiology, “Obesity-induced blood-brain-barrier dysfunction during postnatal development”
- Yu Kuei Lin, MD, Assistant Professor, Internal Medicine - MEND and Melissa DeJonckheere, PhD, Assistant Professor, Family Medicine, “Determining Barriers to Optimal Hypoglycemia Self-management in Adults with Type 1 Diabetes Using Advance Diabetes Technologies”
- Manjunath (Amit) Pai, PharmD, Professor and Chair, Clinical Pharmacy and Amy Rothberg, MD, PhD, Clinical Professor, Internal Medicine - MEND, “Engineering a Type 2 Diabetes Precision Drug Dosing Model”
2020
- Monica Dus, PhD, Assistant Professor, Molecular, Cellular, and Developmental Biology, Life Sciences Institute and Carrie Ferrario, PhD, Professor, Department of Pharmacology, University of Michigan “Reprogramming of dopamine neuron identity with diet-induced obesity”
- Jacob M. Haus, MS, PhD, Associate Professor, School of Kinesiology at the University of Michigan; Michael Munson DPM, Assistant Professor, Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan; and Crystal Holmes DPM, Clinical Associate Professor, Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, “Non-weight bearing exercise for accelerated healing of diabetic foot ulcers”
2019
- Ormond MacDougald, PhD, John A Faulkner Collegiate Professor of Physiology, Professor of Molecular and Integrative Physiology and Professor of Internal Medicine, University of Michigan, and Elif Oral, MD, Professor of Internal Medicine, University of Michigan, “Mechanisms by which lamin A/C deficiency causes loss of adipose tissues”
2018
- Mehboob Hussain, MD, Professor, Internal Medicine - MEND, University of Michigan; Sunitha Nagrath, PhD, Associate Professor, Chemical Engineering, University of Michigan; and Deepak Nagrath, PhD, Associate Professor, Biomedical Engineering, University of Michigan, “In vivo ß-cell specific exosome identification and characterization in diabetes mellitus”
- Jason S. Knight, MD, PhD, Assistant Professor, Internal Medicine-Rheumatology, University of Michigan, and Subramaniam Pennathur, MD, Norman Radin Professor of Nephrology, Professor, Internal Medicine and Molecular & Integrative Physiology, University of Michigan, “Role of neutrophil extracellular traps in diabetic cardiovascular disease”
- Bethany B. Moore, PhD, Galen B. Toews MD Collegiate Professor of Pulmonary & Critical Care Medicine, Professor, Internal Medicine and Microbiology & Immunology, and Director, Doctoral Program in Immunology, University of Michigan, and Katherine A. Gallagher, MD, John R. Pfeifer Collegiate Professor of Vascular Surgery, Associate Professor, Surgery, “Prostaglandin E2 synthesis alters macrophage function to promote inflammation and impair diabetic wound healing”
2017
- Robert O’Rourke, MD, Associate Professor, Surgery, and Lonnie Shea, PhD, Professor and Chair, Department of Biomedical Engineering, “Engineered adipose tissue-bioscaffolds as a therapeutic tool for type 2 diabetes”.
- Amy Rothberg, MD, Associate Professor, Internal Medicine, and Andrew Schrepf, PhD, Research Investigator, Anesthesiology, “The impact of calorie restriction and weight loss on inflammation and centralized pain in individuals at risk for diabetes”.
2016
- Jennifer Harder, MD, Clinical Assistant Professor, Internal Medicine-Nephrology, Cristina Cebrian-Ligero, PhD, Clinical Lecturer, Internal Medicine-Gastroenterology, and Edgar Otto, PhD, Research Assistant Professor, Internal Medicine-Nephrology “Modeling diabetic kidney disease using kidney organoids generated from human iPSC”.
- Jiandie Lin, PhD, Associate Professor, Cell & Developmental Biology, Life Sciences Institute, Katsuo Kurabayashi, PhD, Professor, Mechanical Engineering and Electrical Engineering, and Jun Li, PhD, Associate Professor, Human Genetics, “Elucidating the landscape of liver cell heterogeneity in normal and insulin resistant states by single cell RNA sequencing”.
2015
- Tae-Hwa Chun, MD, Internal Medicine-Metabolism, Endocrinology, and Diabetes, University of Michigan and Shuichi Takayama, PhD, Biomedical Engineering, College of Engineering, University of Michigan, “Developing human adipose tissue on-a-chip (Fat Chip)”.
2014
- Jun Hee Lee, PhD, Assistant Professor, Molecular and Integrative Physiology and Uhn-Soo Cho, PhD, Assistant Professor, Biologic Chemistry, “Biochemical basis for Sestrin2 in metabolism”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).
- Brian Callaghan, MD, Assistant Professor, Neurology and Justin Dimick, MD, MPH, Associate Professor, Surgery, “The association between the metabolic syndrome and neurologic outcomes in a bariatric surgery population.”
2013
- Steven R Buchman, MD, M Haskell Newman Collegiate Professor of Plastic Surgery, Karl J Jepsen, PhD, Glacy Family Scholar, Professor, Associate Chair for Research, Orthopaedic Surgery, and Ernestina Schipani, MD, PhD, Professor, Endocrinology, “Remediating diabetes-impaired bone fracture with Deferoxamine”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).
- Blake Roessler, MD, Professor of Internal Medicine - Rheumatology, Crystal Holmes, D.P.M., Clinical Assistant Professor, Internal Medicine - Metabolism, Endocrinology and Diabetes, and Bin Nan, PhD, Professor, Biostatistics, “Point-of-care bone composition measurements for early-stage detection of osteomyelitis in the diabetic foot”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).
2011
- Steven K. Lundy, PhD, Research Assistant Professor, Department of Internal Medicine, and Massimo T Pietropaolo, MD, Professor of Internal Medicine, Pediatrics and Communicable Diseases, and Microbiology and Immunology, “Targeting killer and regulatory B lymphocyte function in IDDM”
- Joshua D Stein, MD, Assistant Professor of Ophthalmology and Visual Sciences, and David W. Hutton, PhD, John G. Searle Assistant Professor of Health Management and Policy, School of Public Health and Assistant Professor of Industrial Operations, College of Engineering, “Assessing the cost effectiveness of different interventions for clinically significant diabetes macular edema”
2010
- Steve Lentz, PhD, Research Assistant Professor, Department of Internal Medicine, Division of MEND and Roni M Shtein, MD, Assistant Professor, Department of Ophthalmology, “In vivo corneal confocal microscopy for non-invasive assessment of diabetic peripheral neuropathy”
- Amy Rothberg, MD, Clinical Assistant Professor, Department of Internal Medicine, Division of MEND and Jon-Kar Zubieta, MD, PhD, Phil F. Jenkins Research Professor of Depression, Professor of Psychiatry and Radiology and Research Professor, Molecular and Behavioral Neuroscience Institute, “Neurohormonal & behavioral correlates of obesity”
2009
- Eva L Feldman, MD, PhD, DeJong Professor of Neurology and Matthias Kretzler, MD, Associate Professor, Internal Medicine, and Hosagrahar V. Jagadish, PhD, Collegiate Professor of Electrical Engineering and Computer Science, “Biomarkers of diabetic microvascular complications: A bioinformatics approach to human samples”
- Catherine Kim MD, MPH, Assistant Professor, Department of Internal Medicine and Obstetrics and Gynecology and Caroline Richardson, MD, Assistant Professor, Department of Family Medicine, “Pedometers in gestational diabetes”
- Meng Hee Tan, MD, Clinical Professor, Internal Medicine, and David Hanauer, MD, MS, Clinical Professor, Department of Pediatrics and Communicable Diseases, “Creating a diabetes research registry to enhance recruitment of patients in clinical trials and studies at University of Michigan”
2008
- Elif Oral, MD, Assistant Professor, Internal Medicine and John D. Birkmeyer, MD, Professor, General Surgery, “Effect of dietary macrocomposition on non-alcoholic fatty liver disease in bariatric surgery candidates.” Jointly funded by the MDRC, the Michigan Comprehensive Diabetes Center (MCDC) and the Michigan Institute for Clinical and Health Research (MICHR).
2007
- Annette Chang, MD, Internal Medicine, Metabolism, Endocrinology & Diabetes and Michael Kilbourn, PhD, Radiology, “Evaluation of human pancreatic B-cell mass with [11C] dihydrotetrabenazine (DTBZ) Radioligand”
2006
- Martin G Myers, MD, PhD, Internal Medicine, Metabolism, Endocrinology & Diabetes, and Robert Thompson, PhD, Psychiatry, were awarded the MCDC/MDRC DISP award for, “Genomic analysis of novel leptin-regulated neural metabolic pathways.”