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MNORC Pilot/Feasibility URM Grants

Michigan Nutrition Obesity Research Center (MNORC)
Due Date: 5PM, Friday, April 7, 2023

Purpose

The purpose of the MNORC Pilot /Feasibility (P/F) Grant Program is to promote research on the biological and behavioral determinants of obesity, and to develop interventions to reduce obesity and its disease sequelae using basic, clinical, or population approaches. This specific P/F program’s aim is to enable Underrepresented Minority Backgrounds* postdoctoral fellows and early-stage investigators to generate sufficient preliminary information for a successful application for major research funding from NIH or other national granting agencies. 

Grant proposals may be in areas of basic biomedical research (animal or human models) or in clinical, epidemiological, or translational research, e.g., interventions in clinical or population-based setting. Grant proposals involving cross-disciplinary expertise, faculty from different UM schools, and that utilize the core laboratories of the MNORC are especially encouraged. 

Eligibility

Individuals who have early stage full-time instructional, clinical, research faculty or postdoctoral fellow positions at the University of Michigan are eligible to apply as Principal Investigators of P/F proposals. Eligible applicants must be early-stage investigators (5 years from first appt) and/or postdoctoral fellows from Underrepresented Minority Backgrounds* interested in nutrition, metabolism, or obesity from University of Michigan (all campuses) are eligible to apply. 

Successful applicants who receive funding will be required to acknowledge the MNORC funding (P30 DK089503) on all resultant publications, as well as reporting periodically on progress and attending the MNORC Annual Symposium to present the results of the funded project. 

*https://diversity.nih.gov/about-us/population-underrepresented

Questions? Please contact Sandra Wankel 763-9312 wankel@umich.edu

For more information and to apply, visit Competition Space

Pilot & Feasibility Grants Past Awardees

2022-2023 P/F Grant Awards
  • Prashant Singh, MBBS, Assistant Professor of Internal Medicine GI and Hepatology: A randomized controlled trial comparing clinical efficacy of Mediterranean diet and low FODMAP diet in patients with IBS ($49,500)
  • Andriy Myronovych, MD, PhD, Assistant Research Scientist of Surgery: Hepatic Steatosis and Liver Regeneration after Vertical Sleeve Gastrectomy/Partial Hepatectomy in Diet Induced Obese Mice: The Role of FGF15 ($50,000)
  • Brigid Gregg, MD, Assistant Professor of Pediatric Endocrinology: Changes in human milk nutrition as a complication of diabetes in pregnancy ($50,000)
2021 P/F Grant Awards
  • Monica Dus, PhD, Assistant Professor of Molecular, Cellular and Developmental Biology, LSA: "Regulation of insulin biosynthesis and secretion by m6A mRNA Methylation." ($45,000)
  • Melissa Elafros, MD, PhD, Instructor in Neurology, Medical School: "The Flint Neuropathy Study." ($15,000)
2021 URM P/F Grant Awards
  • Cristina Saenz de Miera Patin, PhD, Research Fellow, Molecular and Integrative Physiology, Medical School: "Prenatal photoperiodic programming of the developing metabolic hypothalamus." ($45,000)
  • Sonya Wolf-Fortune, PhD, Research Fellow, Molecular and Integrative Physiology, Medical School: "Dysregulation of keratinocyte/macrophage axis in obesity driven diabetic wounds." ($45,000)
2020 P/F Grant Awards
  • Eric Buras, MD, PhD, Assistant Professor, Internal Medicine MEND: "Thrombospondin-1 promotes fibro-adipogenic remodeling and contractile dysfunction of the diaphragm in obesity" ($45,000)
  • Kendrin Sonneville, ScD, Assistant Professor, Nutritional Sciences, School of Public Health: "Piloting the impact of an intuitive eating-based workplace wellness program" ($45,000)
2019 P/F Grant Awards
  • Erica Jansen, Research Assistant Professor, Nutritional Sciences: "Circadian gene DNA methylation as a predictor of 10-year BMI gains among women" ($25,000)
  • Alla Karnovsky, Research Associate Professor, DCMB: "Exploring Diet/Lipidome Interactions to Understand the Development of Adverse Cardiometabolic Phenotypes in the SWAN Cohort." ($25,000)
  • Laura Saslow, Assistant Professor, School of Nursing: "Piloting the impact of a carbohydrate-reduced eating pattern for non-alcoholic fatty liver disease" ($50,000)
2018 P/F Grant Awards
  • Daniel Lawrence, PhD, Professor, Internal Medicine – Cardiology: "Metabolic insults, the neurovascular unit and Alzheimer’s" ($50,000)
  • Yewei Ji, PhD, Research Investigator, Molecular and Integrative Physiology: "Toll-like Receptors Act as Brakes on Adaptive β-cell Mass Expansion" ($25,000)
  • Anna Mathew, MD, Assistant Professor, Internal Medicine – Nephrology: "Metabolic approach to Understanding the Role of Eicosanoids in Salt Sensitivity in CKD" ($25,000)
2017 P/F Grant Awards
  • Charles Evans, PhD, Research Assistant Professor, Internal Medicine – Metabolism, Endocrinology & Diabetes: “Differentiating intrinsic and exercise training-responsible contributions to exercise capacity, obesity, and metabolic health” ($38,000)
  • Xin (Tony) Tong, MD, PhD, Research Assistant Professor, Molecular & Integrative Physiology: “Role and mechanisms of E4BP4 in high-fat diet-induced liver steatosis” ($38,000)
  • Abhijit Naik, MBBS, Internal Medicine – Nephrology: "Effect of moderate caloric restriction on glomerular growth after kidney transplantation" ($23,441)
2016 P/F Grant Awards
  • Kanakadurga Singer, MD, Assistant Professor, Pediatrics: “Probing sex differences in diet induced inflammation through profiling of hematopoietic progenitors” ($45,000)
  • Marianna Sadagurski, PhD, Assistant Research Professor, Internal Medicine, Geriatric and Palliative Medicine: “Growth hormone receptor modulates glucose homeostasis in nutrient-sensing leptin receptor expressing neurons” ($10,000 small grant)
  • Raymond Trievel, PhD, Associate Professor, Biological Chemistry: “Characterization of the Molecular Functions of the Obesity-linked Protein Nocturnin” ($45,000)
2015 P/F Grant Awards
  • Jun Wu, PhD, Assistant Professor, Life Sciences Institute, Molecular and Integrative Physiology: “Beige fat-specific regulation in mice and humans” ($25,000)
  • Monica Dus, PhD, Assistant Professor, Molecular, Cellular and Developmental Biology (MCDB): “Metabolites as key regulators of feeding states” ($25,000)
  • Wei Perng, PhD, MPH, Research Assistant Professor, Nutritional Sciences: “Metabolomic patterns and development of metabolic risk in US and Mexican children” ($25,000)
  • Ingrid Bergin, DVM, MS, Assistant Professor, Unit for Laboratory Animal Medicine: “Effects of calcium and multi-mineral supplementation on gut microbes and microbially-derived metabolites in patients at risk for colon cancer” ($25,000)
2014 P/F Grant Awards
  • Robert W O'Rourke, Associate Professor of Surgery, Medical School: "glutamine as substrate for de novo lipogenesis in adipocyte-pancreatic cancer metabolic crosstalk- a pilot study" ($33,000)
  • Christa Patterson, Research Investigator, Internal Medicine, Medical School: "Role of Atf3 in central leptin regulation of physiology and neuronal function" ($33,000)
  • Hiroyuki Mori, Research Investigator, Molecular and Integrative Physiology, Medical School: "Role of Wnt11 as a mediator of HIF-1α effects in adipose tissue biology" ($33,000)
  • Elizabeth Speliotes, Assistant Professor of Internal Medicine and Assistant Professor of Computational Medicine and Bioinformatics, Medical School: "NAFLD Metabolomics" ($25,000)
2013 P/F Grant Awards
  • Rebecca Hasson, PhD, Assistant Professor (School of Kinesiology): "Stress-induced eating behavior: implications for pediatric obesity disparities in Latino and African-American Youth" ($50,000)
  • Jun Hee Lee, PhD, Assistant Professor (Department of Molecular and Integrative Physiology): "The role of Sestrin1 against obesity-associated muscle metabolic pathologies" ($50,000)
2012 P/F Grant Awards
  • Lei Yin, PhD, Assistant Professor (Dept of Molecular and Integrative Physiology): "Nutrient-dependent Regulation of Molecular Clock" ($50,000)
  • Shanti Eswaran, MD, Clinical Lecturer (Department of Medicine - Division of Gastroenterology): "Low FODMAP diet vs. usual care for patients with irritable bowel syndrom with diarrhea (IBS-D): a randomized, controlled trial and gastroinestinal microbiome analysis" ($50,000)
  • David P. Olson, MD, PhD, Assistant Professor (Pediatrics and Communicable Disease): "The Role of Vasopressin Neurons in Energy Balance" ($50,000)
2011 P/F Grant Awards
  • Ana Baylin, Assistant Professor, Epidemiology: "Fatty Acids and Risk of Overweight in School-Aged Children" ($50,000)
  • Siming Li, Assistant Research Scientist, Life Sciences Institute: "Dissecting transcriptional control of brown adipocyte development through genome-wide functional screen" ($50,000) 
2010 P/F Grant Awards
  • Carey Lumeng, MD, PhD and Susan Woolford, MD, Assistant Professor, Pediatric and Communicable Diseases: "Inflammatory monocytes in childhood obesity" ($33,000)
  • Dana Dolinoy, PhD, Searle Assistant Professor, SPH Environmental Health Science: "In Utero BPA exposure: Effects on metabolic homeostasis mediated by epigenetic labile loci" ($33,000)
  • Jorge A. Iniguez-Lluhi, PhD, Associate Professor, Pharmacology: "Novel bifunctional glucocorticoid receptor ligands with favorable metabolic profiles through the display of novel chemical functionalities" ($33,000) 
2009 P/F Grant Awards
  • David Lombard, MD, PhD, Assistant Professor, Dept of Pathology and Research Professor, Institute of Gerontology: "Role of acetylation in regulating the pyruvate dehydrogenase complex" ($50,000)
  • Julie Lumeng, MD, PhD, Assistant Professor, Pediatric & Comm Diseases, Asst Research Scientist, Center for Human Growth and Development: "Diurnal salivary cortisol in association with cardiovascular risk markers and weight status in low-income preschool-aged children" ($25,000)

Director

Kanakadurga Singer, MA, MD

Kanakadurga Singer, MD

Director, Pilot & Feasibility Grants Program
734-764-5175
ksinger@umich.edu

 

Contact Us

Sandra Wankel, MSA

MNORC Program Manager
734-763-9312
wankel@med.umich.edu

Research Acknowledgement

It is extremely important that our grant is cited in all publications resulting from the use of MNORC services. Our productivity and effectiveness as a center are measured in part by the citation of the grant in published work. Please use the following acknowledgement in your publications:

This work utilized Core Services supported by grant DK089503 of NIH to the University of Michigan.

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