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portrait of Rodica Pop-Busui
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Rodica Busui, Ph.D., M.D.

(She/her/hers)

Chronic complications of diabetes, nephropathy, and cardiovascular disease

Professor Emeritus/a
Michigan Medicine » Internal Medicine » Metabolism, Endocrinology, and Diabetes
rpbusui@umich.edu
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Biography

Rodica Pop-Busui, MD, PhD, is the Larry D. Soderquist Professor of Diabetes, a prominent diabetologist at Michigan Medicine and a recognized leader in the field of diabetes and diabetes complications. She is the Vice Chair for Clinical Research in the Department of Internal Medicine and the Associate Director of Clinical Research, Mentoring and Development of the Elizabeth Caswell Diabetes Institute at the University of Michigan. Her research interests involve chronic complications of diabetes, particularly diabetic peripheral and cardiovascular autonomic neuropathy, as well as diabetic foot complications, diabetic kidney disease and cardiovascular disease, and the design and conduct of traditional and pragmatic clinical trials for patients with diabetes.

Dr. Pop-Busui has published more than 200 peer-reviewed manuscripts and book chapters, and received awards from the American Diabetes Association (ADA) and the University of Michigan. She has chaired the 2017 American Diabetes Association Position Statement on Diabetic Neuropathy, and has served as Chair of the American Diabetes Association Scientific Research Review Clinical and Chair of the ADA Diabetes & Cardiovascular Disease Interest Group. Most recently she has been elected to chair the Precision Prognostic in Type 1 Diabetes Working Group of the American Diabetes Association/European Association for the Study of Diabetes.

She has been PI/CoI and member of the Steering Committee in several landmark diabetes clinical trials including: the NHLBI-funded Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, the NIDDK funded Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications, Preventing Early Renal Loss in Type 1 Diabetes (PERL), Bypass Angioplasty Revascularization Diabetes 2 (BARI- 2D) and Glycemia Reduction Approaches in Type 2 Diabetes-A Comparative Effectiveness Study (GRADE) . In addition, she designed and leads several investigator-initiated studies funded by NIDDK and Pharma to unveil disease modifying agents for diabetic neuropathy and other chronic diabetes complications.

Dr Pop-Busui is the corresponding principal investigator and member of the Steering Committee of the recently established NIDDK Diabetes Foot Consortium and one of the principal investigators of the JDRF Center of Excellence at the University of Michigan .
Dr Pop-Busui had also mentored junior physician scientists and other trainees in their career developments, has implemented and directs the Clinical Trials Academy at the University of Michigan, and is the PI on the Steno North American Fellowship funded by Novo Nordisk Foundation to foster new collaborations and mentoring between physicians scientists from the University of Michigan and the 5 Steno Diabetes Centers in Denmark.

  • BS, College of Mathematics-Physics
  • Ph.D., University of Timisoara, School of Medicine
  • M.D., University of Timisoara, School of Medicine

Research

Dr. Pop-Busui has concentrated her scholarship and research efforts on translational and clinical research focused in understanding the mechanisms of diabetic complications, particularly of diabetic peripheral neuropathy and cardiovascular autonomic neuropathy, and to understand their role in the development of the high cardiovascular risk complicating diabetes. As a result of her efforts, her research has been funded by the National Institute of Health/National Heart, Lung and Blood Institute, the American Diabetes Association, the Juvenile Diabetes Research Foundation, other foundations and industry. She also is and has been a PI or co-PI on several landmark diabetes trials funded by the National Institute of Health, such as the NHLBI-funded Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, the NHLBI-funded Bypass Angioplasty Revascularization Investigation Type 2 Diabetes (BARI 2D) study, and the NIDDK-funded Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC).

Links

Michigan Research Experts Profile Dr. Busui's Website Does high blood sugar worsen COVID-19 outcomes? Program for Clinical Research in Diabetes Care & Complications
In the News
ICYMI: Dialogue with ADA: Addressing Opportunities & Challenges of Preventing Diabetes-Related Amputations
Dr. Rodica Pop-Busui Offers Inspiring Presidential Address at the ADA 83rd Scientific Sessions
Condition Focus
Type 1 Diabetes
Prediabetes
Cardiovascular disease
Type 2 Diabetes
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Population Focus
Low Income
Men
Older Adults (Geriatrics)
Women
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Center, Institute, and Program Affiliations
Caswell Diabetes Institute
Michigan Center for Diabetes Translational Research
Michigan Diabetes Research Center
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Career Track
Clinical Care
Clinical Research
Health Services Research
Translational Research
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Language Proficiency
  • French - Read/Write/Speak

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